Hi, if u're running the game at version 1.00, u can't enable the nvidia TNT mode, I get the black screen showing the red arrows and Cloud too if I do that. Instead, use software rendering if you want to play at version 1.00. FMVs will play at a lagged pace though.
Try using the official 1.02 patch then enable the Nvidia TNT option. Also, if you have RIVAtuner, enable the options for 8 bit palettes and don't try to go beyond 8 FSAA/Anistropy. I get the funny segmented screen when I do that with my card. I'm using a 6600GT on 71.89 drivers by the way.
Hope this helps.